研究者データベース - 根木　滋

ネギ　シゲル NEGI Shigeru
根木　滋

所属同志社女子大学薬学部医療薬学科

職種教授

著書・論文歴
著書	“Non-FokI-based zinc finger nuclease” in Engineered Zinc Finger proteins <Eds. by J. Mackay and D. Segal> 649巻 (共著) 2010/10
論文	Creation and Biological Application of Intelligent Zinc Finger Proteins The Harris Science Review of Doshisha University Vol.63 (No.4),55-62頁 (共著) 2023
論文	A Synthetic Porphyrin as an Effective Dual Antidote against Carbon Monoxide and Cyanide Poisoning The Proceedings of the National Academy of Sciences in press (共著) 2022/12
論文	Highly Ordered Monolayers of an Optically Active Amphiphilic Pyrene Derivative at the Air–Water Interface Bulletin of the Chemical Society of Japan Vol.95 (No.11),1537-1545頁 (共著) 2022/11
論文	Effects of Ca²⁺ concentration, reaction temperature, E105 point mutation, and exogenous metal ion on the transpeptidation reaction of transpetidase Sortase A. Bulletin of Institute for Interdisciplinary Studies of Culture Doshisha Women's College of Liberal Arts Vol.39,141-150頁 (共著) 2022/07
論文	Poly(ADP-ribose) Polymerase 1 Mediates Rab5 Inactivation after DNA Damage International Journal of Molecular Sciences Vol.23 (No.14),1-16頁 (共著) 2022/07
論文	Transpeptidation reaction mediated by ligand- and metal cofactor-substituted Sortase A from Staphylococcus aureus Bulletin of the Chemical Society of Japan Vol.95,1025-1031頁 (共著) 2022/07
論文	Involvement of Trace Metals in the Reduction of Disulfide Bonds by Glutathione. The Harris Science Review of Doshisha University. Vol.63,45-49頁 (共著) 2022/04
論文	Effect of charged-cluster distribution of the ZIF268 zinc finger surface on cell membrane permeability Chemistry Letters in press (共著) 2022
論文	Importance of two-dimensional cation clusters induced by protein folding in intrinsic intracellular membrane permeability RSC Chemical Biology Vol.3,1076-1084頁 2022
論文	Monolayer formation and chiral recognition of binaphthyl amphiphiles at the air–water interface Bulletin of the Chemical Society of Japan in press (共著) 2022
論文	New Role of Biological Trace Metal Elements for the Cooperative Reduction of Protein by Glutathione and its Derivatives Peptide Science 58rd,103-106頁 2021/03
論文	Deciphering the Molecular Mechanism Underlying Oxidation Reactions of Zinc Finger Proteins Using H2O2. Peptide Science 58rd,89-92頁 (共著) 2021
論文	Observation of the Aggregation Process of Oligoarginine and Calf Thymus DNA: Thermodynamic and Morphological Characteristics. Peptide Science 58rd,167-170頁 (共著) 2021
論文	The 89-kDa PARP1 cleavage fragment serves as a cytoplasmic PAR carrier to induce AIF-mediated apoptosis Journal of Biological Chemistry Vol.296,1-13頁 (共著) 2021
論文	Supramolecular Complexation in Biological Media: NMR Study on Inclusion of an Anionic Tetraarylporphyrin into a Per-O-Methylated β-Cyclodextrin Cavity in Serum, Blood, and Urine Chemistry – An Asian Journal Vol.14,3320-3328頁 (共著) 2019
論文	Circadian clock disruption by selective removal of endogenous carbon monoxide Scientific reports Vol.8 (No.11996),1-12頁 (共著) 2018
論文	Detection and Removal of Endogenous Carbon Monoxide by Selective and Cell-permeable Hemoprotein-model Complexes Journal of the American Chemical Society 139,5984-5991頁 (共著) 2017/04/26
論文	Feedback Response to Selective Depletion of Endogenous Carbon Monoxide in the Blood. J Am Chem Soc. 138 (16),5417-5425頁 (共著) 2016/04/18
論文	Efficient cleavage of DNA oligonucleotides by a non-FokI-type zinc　finger nuclease containing one His4-type finger domain derived from the first　finger domain of Sp1 Bioorganic & Medicinal Chemistry Letter Vol.25,p.p. 4074-4077頁 (共著) 2015/10
論文	Intrinsic cell permeability of the GAGA zinc finger protein into HeLa Biochemical and Biophysical Research Communications Vol. 464,pp. 1034-1039頁 (共著) 2015/09
論文	Supramolecular intracellular delivery of an anionic porphyrin by octaarginine-conjugated per-O-methyl-β-cyclodextrin Chemical Communications Vol. 51,pp. 2421-2424頁 (共著) 2015/02
論文	New functions of zinc finger proteins Science and Engineering Review of Doshisha University Vol. 53,pp. 112-117頁 2013/06
論文	Zn(II) Binding and DNA Binding Properties of Ligand-Substituted　CXHH-Type Zinc Finger Proteins Biochemistry 51巻,3342-3348頁 (共著) 2012/04
論文	Rational design of DNA sequence-specific zinc fingers FEBS Letters 586巻,918-923頁 (共著) 2012/03
論文	Specific microfluidic behavior of ternary mixed carrier solvents of water-acetonitrile-ethyl acetate in open-tubular capillary chromatography and the chromatograms Analytical Methods Vol. 4,3884-3890頁 (共著) 2012
論文	An arginine residue instead of a conserved leucine residue in the　recognition helix of the finger 3 of Zif268 stabilizes the domain structure　and mediates DNA binding Biochemistry 150巻,6266-6272頁 (共著) 2011/07
論文	Zinc finger-zinc finger interaction between the transcription factors, GATA-1and Sp1 Biochemical and Biophysical Research Communications, 400巻,625-630頁 (共著) 2010/10
論文	Cytochrome C polymerization by successive domain swapping at the C-termina helix Proceedings of the National Academy of Sciences of the United States of America 107巻,12854-12859頁 (共著) 2010/07
論文	Binding of multivalent anionic porphyrins to V3 loop fragment of HIV-1 and their antiviral activity Chemistry Asian Journa 5巻,825-834頁 (共著) 2010/04
論文	A diatomic molecule receptor that removes CO in a living organism Angewandte Chemie International Edition 49巻,1312-1315頁 (共著) 2010/02
論文	Novel zinc finger nuclease created by combining the Cys2His2- and His4-type zinc finger domains Bioorganic & Medicinal Chemistry Letters Vol.19,2789-2791頁 (共著) 2009/05
論文	Effects of Bulkiness and Hydrophobicity of an Aliphatic Amino Acid in the Recognition Helix of the GAGA Zinc Finger on the Stability of the Hydrophobic Core and DNA Binding Affinity Biochemistry Vol.47,11717-11724頁 (共著) 2008/10
論文	New Redesigned Zinc-Finger Proteins: Design Strategy and Its application Chemistry-A European Journal Vol.14,3236-3249頁 (共著) 2008/04
論文	DNA-binding ability of GAGA zinc finger depends on the nature of amino acids present in theβ-hairpin Biochemistry Vol.46 (No.25),7506-7513頁 (共著) 2007/06
論文	Effect of aromatic amino acid, phenylalanine, substitution in the beta-hairpin region of GAGA zinc finger on DNA binding Peptide Science,166-167頁 (共著) 2006/11
論文	Metal preference and DNA-binding properties of C2H2-type zinc finger peptide from GAGA transcription factor Peptide Science,105-106頁 (共著) 2006/11
論文	Rational design of a porphyrin binding peptide as heme model Peptide Science,103-104頁 (共著) 2006/11
論文	Designer Zinc Finger Proteins: Tools for Creating Artificial DNA-Binding Functional Proteins Accounts of Chemical Research Vol.39 (No.1),45-51頁 (共著) 2006/10
論文	Biomolecular mirror-image recognition: reciprocal chiral-specific DNA binding of synthetic enantiomers of zinc finger domain from GAGA factor Chirality Vol.18 (No.4),254-258頁 (共著) 2006/05
論文	Mirror-image recognition in peptide-DNA interaction Peptide Science Vol.42,93-96頁 (共著) 2005
論文	Site-specific DNA cleavage by artificial zinc finger-type nuclease with cerium-binding peptide Biochem. Biophys. Res. Commun. Vol.330,247-252頁 (共著) 2005
論文	Creation and Characteristics of Unnatural CysHis3-Type Zinc Finger Protein Biochem. Biophys. Res. Commun. Vol.325,432-425頁 (共著) 2004
論文	Protein folding by the effects of macromolecular crowding Protein Sci Vol.13,125-133頁 2004
論文	Metal Coordination and Stacking Effects in Supramolecular Catalysis. Effects of Structural Variations of Copper Complexes for the Hydrolysis of Phosphate Esters TETRAHEDRON LETTERS Vol.43,411-414頁 (共著) 2002
論文	Hydrogen-Bonded Complexes of Carboxylate Anions and Dextrins in an Aprotic Polar Solvent Eur.J.Org.Chem. Vol.43,3689-3694頁 (共著) 2001/09
論文	Effects of Anions in Subphases on Langmuir Monolayer of N,N-Dimethyl-1-octadecanamine Bull. Chem. Soc. Jpn Vol.73 (No.4),977-984頁 (共著) 2000/03
論文	Chiral recognition of 1-(4-quinolyl)ethanol by permethylated α-cyclodextrin Journal of Chemical Research,750-751頁 1999/12
論文	Chiral recognition of an anionic tetrahelicene by native cyclodextrins. Enantioselectivity dominated by location of a hydrophilic group of the guest in a cyclodextrin cavity Journal of the Chemical Society, Perkin Transactions 2 2 (1),15-22頁 1999/01
論文	Self-Aggregation of Cationic Porphyrins in Water. Can Stacking Interaction Overcome Electrostatic Repulsive Force? Journal of Physical Chemistry A 1998/08
論文	Optical resolution of 1- arylethanols using transesterification catalyzed by lipases Enantiomer Vol. 2,261-266頁 (共著) 1997/10
論文	Chiral Recognition of Tetrahelicene Dicarboxylic Acid by Linear Dextrins Chemistry Letters 1997/04
論文	Recognition of helicity by native cyclodextrins. Highly enantioselective complexation of tetra helicene dicarboxylic acid with α-cyclodextrin Chemistry Letters 1997/04
論文	Mechanism for binding to the flexible cavity of permethylated α-cyclodextrin Journal of Inclusion Phenomena and Molecular Recognition in Chemistry 1995/12
その他	新機能性亜鉛フィンガータンパク質のデザインと医学・薬学領域への展開ファルマシア Vol. 43,527-532頁 2007/06
その他	人工亜鉛フィンガーによる遺伝子発現の制御－人工制限酵素から遺伝子治療まで化学 Vol. 61,68-69頁 2006/08
その他	伝子を標的とする亜鉛フィンガーのタンパク質工学、人工亜鉛フィンガータンパク質の創製と機能化学工業 2006/07