研究者データベース - 松本　健次郎

マツモト　ケンジロウ MATSUMOTO Kenjiro
松本　健次郎

所属同志社女子大学薬学部医療薬学科

職種教授

著書・論文歴
著書	「医学のあゆみ：TRPチャネルのすべて」 270巻10号 (共著) 2019/09
著書	「Functional Dyspepsia：Evidences in Pathophysiology and Treatment」 (共著) 2018/08
著書	「トワイクロス先生のがん緩和ケア処方薬第2版:：薬効・薬理と薬の使い方」 (共著) 2017/06
著書	「Kratom and Other Mitragynines」 (共著) 2015/04
著書	「機能性ディスペプシア　日本人に適した診療を求めて」 (共著) 2014/10
著書	「Capsaicin-Sensitive Neural Afferentation and the Gastrointestinal Tract」 (共著) 2014/07
著書	「ファーマコセラピー－病態生理からのアプローチ－」 (共著) 2007/08
論文	「Repeated psychological stress, chronic vicarious social defeat stress, evokes irritable bowel syndrome-like symptoms in mice」『Frontiers in Neuroscience.』 Vol.16,pp.9931327 (共著) 2022/10
論文	「A quinazoline-based bromodomain inhibitor, CN210, ameliorates indomethacin-induced ileitis in mice by inhibiting inflammatory cytokine expression」『Drug Development Research』 Vol.82(8),pp.1235-1246頁 (共著) 2021/12
論文	「Juvenile social defeat stress exposure favors in later onset of irritable bowel syndrome-like symptoms in male mice」『Scientific Reports』 Vol.11(1),pp.16276 (共著) 2021/08
論文	「Protective effect of TRPM8 against indomethacin-induced small intestinal injury via the release of calcitonin gene-related peptide in mice」『Biological and Pharmaceutical and Bulletin』 Vol.44(7),pp.947-957頁 (共著) 2021/07
論文	「Role of transient receptor potential vanilloid subtype 2 in lower oesophageal sphincter in rat acid reflux oesophagitis」『Journal of Pharmacological Sciences』 Vol.146(3),pp.125-135頁 (共著) 2021/07
論文	「炎症性腸疾患モデルにおけるTRPチャネルの役割」『細胞』 Vol.53(4),pp.54-55頁 (共著) 2021/04
論文	「The rodent model of impaired gastric motility induced by allyl isothiocyanate, a pungent ingredient of wasabi, to evaluate therapeutic agents for functional dyspepsia」『Journal of Pharmacological Sciences』 Vol.145(1),pp.122-129頁 (共著) 2021/01
論文	「Leukotriene B4 receptor type 2 accelerates the healing of intestinal lesions by promoting epithelial cell proliferation」『Journal of Pharmacology and Experimental Therapeutics』 Vol.373(1),pp.1-9頁 (共著) 2020/04
論文	「NOX1/NADPH oxidase in bone marrow-derived cells modulates intestinal barrier function」『Free Radical Biology and Medicine』 Vol.147,pp.90-101頁 (共著) 2020/02
論文	「Role of transient receptor potential vanilloid subtype 4 in the regulation of azoymethane/dextran sulphate sodium-induced colitis-associated cancer in mice」『European Journal of Pharmacology』 Vol.867,pp.172853 (共著) 2020/01
論文	「G protein-coupled receptor 40 activation ameliorates dextran sulfate sodium-induced colitis in mice via the upregulation of glucagon-likepeptide-2」『Journal of Pharmacological Sciences』 Vol.140(2),pp.144-152頁 (共著) 2019/06
論文	「Transient receptor potential vanilloid 4 mediates sour taste sensing via type III taste cell differentiation」『Scientific Reports』 Vol. 9(1),pp.6689 (共著) 2019/04
論文	「Characterization of the gastric motility response to human motilin and erythromycin in human motilin receptor-expressing transgenic mice」『PLoS One』 Vol.14(2),pp.0205939 (共著) 2019/02
論文	「マウス炎症性腸疾患モデルにおける血管内皮TRPV4の発現増大と病態への関与」『日本薬理学雑誌』 Vol.152(4),pp.170-174頁 (共著) 2018/10
論文	「消化管スパイスセンサーとその機能 : 辛味は胃腸でも味わう」『薬学雑誌』 Vol.138(8),pp.1003-1009頁 (共著) 2018/08
論文	「Role of transient receptor potential melastatin 2 in surgical inflammation and dysmotility in a mouse model of post-operative ileus」『American Journal of Physiology Gastrointestestinal Liver Physiology』 Vol.315(1),pp.G104-116頁 (共著) 2018/07
論文	「Transient receptor potential vanilloid 1 and transient receptor potential ankyrin 1 contribute to the progression of colonic inflammation in dextran sulfate sodium-induced colitis in mice: Links to calcitonin gene-related peptide and substance P」『Journal of Pharmacological Sciences』 Vol.36(3),pp.121-132頁 (共著) 2018/03
論文	「ELR+ chemokine-mediated neutrophil recruitment is involved in 2,4,6-trinitrochlorobenzene-induced contact hypersensitivity」『Clinical and Experimental Pharmacology and Physiology』 Vol.45(1),pp.27-33頁 (共著) 2018/01
論文	「Transient receptor potential vanilloid 4 channel regulates vascular endothelial permeability during colonic inflammation in dextran sulphate sodium-induced murine colitis」 British Journal of Pharmacology』 Vol.175(1),pp.84-99頁 (共著) 2018/01
論文	「Probiotic Bifidobacterium bifidum G9-1 attenuates 5-fluorouracil-induced intestinal mucositis in mice via suppression of dysbiosis-related secondary inflammatory responses」『Clinical and Experimental Pharmacology and Physiology』 Vol.44(10),pp.1017-1025頁 (共著) 2017/10
論文	「Apoptosis, dysbiosis and expression of inflammatory cytokines are sequential events in the development of 5-fluorouracil-induced intestinal mucositis in mice」『Basic & Clinical Pharmacology & Toxicology』 Vol. 121(3),pp.159-168頁 (共著) 2017/09
論文	「G protein-coupled receptor 35 contributes to mucosal repair in mice via migration of colonic epithelial cells」『Pharmacological Research』Vol Vol.123,pp.27-39頁 (共著) 2017/09
論文	「Curcumin inhibits epigen and amphiregulin upregulated by 2,4,6-trinitrochlorobenzene associated with attenuation of skin swelling」『Inflammation Research』 Vol. 66(8),pp.663-678頁 (共著) 2017/08
論文	「Role of transient receptor potential melastatin 2 (TRPM2) channels in visceral nociception and hypersensitivity」『Experimental Neurology』 Vol. 285(Pt A),pp.41-50頁 (共著) 2016/11
論文	「5-HT3 receptors promote colonic inflammation via activation of substance P/neurokinin-1 receptors in dextran sulphate sodium-induced murine colitis」『British Journal of Pharmacology』 Vol.173(11),pp.1835-1849頁 (共著) 2016/06
論文	「Differences in the morphine-induced inhibition of small and large intestinal transit: Involvement of central and peripheral μ-opioid receptors in mice」『European Journal of Pharmacology』Vol.771 pp.220～228,pp.220-228頁 (共著) 2016/03
論文	「TRPチャネルと内臓痛」『日本薬理学雑誌』 Vol.146(4),pp.1165-1170頁 (共著) 2015/12
論文	「L-Cysteine/D,L-homocysteine-regulated ileum motility via system L and B°,+ transporter: Modification by inhibitors of hydrogen sulfide synthesis and dietary treatments」『European Journal of Pharmacology』 Vol.764,pp.471-479頁 (共著) 2015/10
論文	「Therapeutic action of 5-HT3 receptor antagonists targeting peritoneal macrophages in post-operative ileus」『British Journal of Pharmacology』 Vol.172(4),pp.1136-1147頁 (共著) 2015/02
論文	「Distribution of transient receptor potential cation channel subfamily V member 1-expressing nerve fibers in mouse esophagus」『Histochemical Cell Biology』 Vol.142(6),pp.635-644頁 (共著) 2014/12
論文	「炎症性腸疾患モデル動物における温度感受性受容体TRPV1とセロトニンシグナリングの変化」『薬学雑誌』 Vol.134(11),pp.1165-1170頁 (単著) 2014/10
論文	「Circular muscle contraction in the mice rectum plays a key role in morphine-induced constipation」『Neurogastroenterology & Motility』 Vol.26(10),pp.1396-1407頁 (共著) 2014/09
論文	「Neutrophil recruitment is critical for 5-fluorouracil-induced diarrhea and the decrease in aquaporins in the colon」『Pharmacological Research』 Vol.87,pp.71-79頁 (共著) 2014/09
論文	「TRPM8 has a key role in experimental colitis-induced visceral hyperalgesia in mice」『Neurogastroenterology & Motility』 Vol.26(8),pp.1112-1121頁 (共著) 2014/08
論文	「Orally active opioid μ/δ dual agonist MGM-16, a derivative of the indole alkaloid mitragynine, exhibits potent antiallodynic effect on neuropathic pain in mice」『Journal of Pharmacology and Experimental Therapeutics』 Vol.348(3),pp.383-392頁 (共著) 2014/03
論文	「Bee venom phospholipase A2-induced phasic contractions in mouse rectum: independent roles of eicosanoid and gap junction proteins and their loss in experimental colitis」『European Journal of Pharmacology』 Vol.718(1-3),pp.314-322頁 (共著) 2013/10
論文	「Mechanisms that underlie μ-opioid receptor agonist-induced constipation; differential involvement of μ-opioid receptor sites and responsible regions」『Journal of Pharmacology and Experimental Therapeutics』 Vol.347(1),pp.91-99頁 (共著) 2013/08
論文	「Neuronal nitric oxide synthase-derived nitric oxide is involved in gastric mucosal hyperemic response to capsaicin in rats」『Pharmacology』 Vol.92(1-2),pp.66-70頁 (共著) 2013/08
論文	「Increased expression of 5-HT3 and NK1 receptors in 5-fluorouracil-induced mucositis in mouse jejunum」『Digestive Diseases and Sciences』 Vol.58(12),pp.3440-3451頁 (共著) 2013/05
論文	「5-HT3 receptor antagonists ameliorate 5-fluorouracil-induced intestinal mucositis by suppression of apoptosis in mice intestinal crypt cells」『British Journal of Pharmacology』 Vol.168(6),pp.1388-1400頁 (共著) 2013/03
論文	「5-Fluorouracil induces diarrhea with changes in the expression of inflammatory cytokines and aquaporins in mouse intestines」『PLoS One』 Vol.8(1),pp.e54788 (共著) 2013/01
論文	「Dietary agonists of TRPV1 inhibit gastric acid secretion in mice」『Planta Medica』 Vol.78(17),pp.1801-1806頁 (共著) 2012/11
論文	「Dual role of serotonin in the pathogenesis of indomethacin-induced small intestinal ulceration: pro-ulcerogenic action via 5-HT3 receptors and anti-ulcerogenic action via 5-HT4 receptors」『Pharmacological Research』 Vol.66(3),pp.226-234頁 (共著) 2012/09
論文	「Experimental colitis alters expression of 5-HT receptors and transient receptor potential vanilloid 1 leading to visceral hypersensitivity in mice」『Laboratory Investigation』 Vol.92(5),pp.769-782頁 (共著) 2012/05
論文	「Subdiaphragmatic vagotomy induces a functional change in visceral Aδ primary afferent fibers in rats」『Synapse』 Vol.66(4),pp.369-371頁 (共著) 2012/04
論文	「Dysfunction of neurogenic VIP-mediated relaxation in mouse distal colon with dextran sulfate sodium-induced colitis」『Pharmacological Research』 Vol.65(2),pp.204-212頁 (共著) 2012/02
論文	「Subdiaphragmatic vagotomy increases the sensitivity of lumbar Aδ primary afferent neurons along with voltage-dependent potassium channels in rats」『Synapse』 Vol.66(2),pp.95-105頁 (共著) 2012/02
論文	「Decrease of guanylyl cyclase β1 subunit and nitric oxide (NO)-induced relaxation in mouse rectum with colitis and its reproduction on long-term NO treatment」『Naunyn-Schmiedeberg's Archives of Pharmacology』 Vol.385(1),pp.81-94頁 2012/01
論文	「ワサビ受容体TRPA1の胃機能における役割－バニロイド受容体TRPV1との比較」『G.I. Research』 Vol.19(3),pp.210-216頁 (共著) 2011/06
論文	「Distribution of transient receptor potential vanilloid 1 channel-expressing nerve fibers in mouse rectal and colonic enteric nervous system: relationship to peptidergic and nitrergic neurons」『Neuroscience』 Vol.172,pp.518-534頁 (共著) 2011/02
論文	「Inhibitory effect of Iboga-type indole alkaloids on capsaicin-induced contraction in isolated mouse rectum」『Journal of Natural Medicine』 Vol.65(1),pp.157-165頁 (共著) 2011/01
論文	「消化管におけるセロトニンシグナリングシステムと内蔵知覚」『G.I. Research』 Vol.18(5),pp.387-393頁 (共著) 2010/10
論文	「Neurogenic contraction of mouse rectum via the cyclooxygenase pathway: Changes of PGE2-induced contraction with dextran sulfate sodium-induced colitis」『Pharmacological Research』 Vol.61(1),pp.48-57頁 (共著) 2010/01
論文	「Subdiaphragmatic vagotomy promotes nociceptive sensitivity of deep tissue in rats」『Neuroscience』 Vol.164(3),pp.1252-1262頁 (共著) 2009/12
論文	「Localization of TRPV1 and contractile effect of capsaicin in mouse large intestine: high abundance and sensitivity in rectum and distal colon」『American Journal of Physiology Gastrointestinal and Liver Physiology』 Vol.297(2),pp.G348-360頁 (共著) 2009/08
論文	「Validation of 13C-acetic acid breath test by measuring effects of loperamide, morphine, mosapride, and itopride on gastric emptying in mice」『Biological and Pharmaceutical and Bulletin』 Vol.31(10),pp.1917-1922頁 (共著) 2008/10
論文	「温度と辛味を感じる受容体：消化管にとってよい受容体か？悪い受容体か」『G.I. Research,』 Vol.16(5),pp.403-410頁 (共著) 2008/10
論文	「Chemical constituents of Aristolochia constricta: antispasmodic effects of its constituents in guinea-pig ileum and isolation of a diterpeno-lignan hybrid」『Journal of Natural Products』 Vol.71(7),pp.1167-1172頁 (共著) 2008/08
論文	「MGM-9[ (E)-methyl 2-(3-ethyl-7a,12a-(epoxyethanoxy)-9-fluoro- 1,2,3,4,6,7,12,12b-octahydro-8-methoxyindolo[2,3-a]quinolizin-2-yl)- 3-methoxyacrylate, a derivative of the indole alkaloid mitragynine: a novel dual-acting mu- and kappa-opioid agonist with potent antinociceptive and weak rewarding effects in mice」『Neuropharmacology』 Vol.55(2),pp.154-165頁 (共著) 2008/08
論文	「Contractile effect of TRPA1 receptor agonists in the isolated mouse intestine」『European Journal of Pharmacology』Vol.576(1-3),pp,143-150頁 (共著) 2007/12
論文	「Effect of capsaicin via TRPV1 in isolated mouse lower gastrointestinal tract and the influence of neuronal stress」『Autonomic Neuroscience』 Vol.135(1-2),pp.96-97頁 (共著) 2007/05
論文	「An emulsion of sulfoquinovosylacylglycerol with long-chain alkanes increases its permeability to tumor cells」『Journal of Membrane Biology』 Vol.213(1),pp.11-18頁 (共著) 2006/12
論文	「Involvement of μ-opioid receptors in antinociception and inhibition of gastrointestinal transit induced by 7-hydroxymitragynine, isolated from Thai herbal medicine Mitragyna speciosa」『European Journal of Pharmacology』 Vol.549(1-3),pp.63-70頁 (共著) 2006/11
論文	「New procedure to mask the 2,3-π bond of the indole nucleus and its application to the preparation of potent opioid receptor agonists with a Corynanthe skeleton」『Organic Letters』 Vol.8(25),pp.5705-5708頁 (共著) 2006/11
論文	「タイ国薬用植物 Mitragyna Speciosa成分7-hydroxymitragynineのオピオイド鎮痛作用に関する薬理学的研究」博士論文（千葉大学） (単著) 2006/08
論文	「Partial agonistic effects of 9-hydroxycorynantheidine on μ-opioid receptor in the guinea-pig ileum」『Life Sciences』 Vol.78(19),pp.2265-2271頁 (共著) 2006/04
論文	「Effective form of sulfoquinovosyldiacyglycerol (SQDG) vesicles for DNA polymerase inhibition」『Colloids and Surfaces B』 Vol.46(3),pp.175-181頁 (共著) 2005/12
論文	「Antinociception, tolerance and withdrawal symptoms induced by 7-hydroxymitragynine, an alkaloid from the Thai medicinal herb Mitragyna speciosa」『Life Sciences』 Vol.78(1),pp.2-7頁 (共著) 2005/11
論文	「Inhibitory effect of mitragynine, an analgesic alkaloid from Thai herbal medicine, on neurogenic contraction of the vas deferens」『Life Sciences』 Vol.78(2),pp,187-194頁 (共著) 2005/11
論文	「Indole alkaloids of a Thai medicinal herb, Mitragyna speciosa, that has opioid agonistic effect in guinea-pig ileum」『Planta Medica』 Vol.71(3),pp.231-236頁 (共著) 2005/03
論文	「Monolayer membranes and bilayer vesicles characterized by α- and β-anomer of sulfoquinovosyldiacyglycerol (SQDG)」『Chemistry and Physics of Lipids』 Vol.133(2),pp.203-214頁 (共著) 2005/02
論文	「Mechanism of the immunosuppressive effect in vivo of novel immunosuppressive drug beta-SQAG9, which inhibits the response of the CD62L+ T-cell subset」『Transplantation proceedings』 Vol.37(1),pp.139-142頁 (共著) 2005/01
論文	「Design of vesicles of 1,2-di-O-acyl-3-O-(beta-D-sulfoquinovosyl)-glyceride bearing two stearic acids (β-SQDG-C18), a novel immunosuppressive drug」『Biochemical Pharmacology』 Vol.68(12),pp.2379-2386頁 (共著) 2004/12
論文	「Inhibition of CD62L+ T-cell response in vitro via a novel sulfo-glycolipid, β-SQAG9 liposome that binds to CD62L molecule on the cell surface」『Cellular Immunology』 Vol.232(1-2),pp.105-115頁 (共著) 2004/11
論文	「Antinociceptive effect of 7-hydroxymitragynine in mice: Discovery of an orally active opioid analgesic from Thai medicinal herb Mitragyna speciosa」 Life Sciences』 Vol.74(17),pp.2143-2155頁 (共著) 2004/03
論文	「Studies on the synthesis and opioid agonistic activities of mitragynine-related indole alkaloids: discovery of opioid agonists structurally different from other opioid ligands」『Journal of Medicinal Chemistry』 Vol.45(9),pp.1949-1956頁 (共著) 2002/04